I came across this article and am absolutely amazed at the reception this natural supplement has received from the medical fraternity. Could this possibly now, once and for all, show that natural products play a significant part in health?
Food Supplement Linked to
Lower PSA in Prostate Cancer
June 10, 2013
CHICAGO, Illinois — A
commercially available food supplement that contains pomegranate, broccoli,
green tea, and turmeric significantly lowers prostate-specific antigen (PSA)
levels, compared with placebo, in patients with prostate cancer, a double-blind
placebo-controlled randomized trial has shown.
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Pomi-T (nature Medical
Products)
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The study results, presented here
at the 2013 Annual Meeting of the American Society of Clinical Oncology (ASCO®), made headlines around the
world and caused the polyphenol-rich supplement, known as Pomi-T (nature
Medical Products), to sell out within hours.
This is a "promising new
therapy," said Tomasz Beer, MD, professor of medicine and director of the
prostate cancer research program at the Oregon Health and Science University in
Portland, during a "highlights of the day" session.
"We have been staggered by
the level of interest...from medical professionals and the public," Marcus
Williams, owner and director of nature Medical Products, told Medscape
Medical News. As soon as the results of this study were released, the
company, based in Porthcawl, South Wales, United Kingdom, received a rush of
orders from customers in Australia, Canada, the United Kingdom, and the United
States.
"It's awesome," the
study's lead investigator, Robert Thomas, MD, a consultant oncologist at
Bedford Hospital and Addenbrooke's Hospital, in the United Kingdom, told Medscape
Medical News.
"We didn't expect such a big
response. People are seeing that this can change practice...because men and
their doctors do look at their PSA as a deciding factor in whether to stop
active management," he explained.
Previous research has shown that
the polyphenols and antioxidants in pomegranate, broccoli, green tea, and
turmeric have individual anticancer properties, but "we believe there's a
synergistic effect in the supplement," said Dr. Thomas.
In addition, the fact that each
ingredient originates from a separate food category (fruit, vegetable, herb, and
spice) might prevent potential adverse effects from the overconsumption of one
particular type of polyphenol, he noted.
In the lab, polyphenols have been
shown to have antiproliferative, antiangiogenic, proadhesion, antimetastatic,
and proapoptotic properties, and notably, they have no phytoestrogenic or
hormonal effects. "We specifically chose to steer away from anything that
might have a hormonal effect."
Because of the supplement's
effect is likely not hormonal, future trials will involve men with different
stages of prostate cancer and those receiving androgen-deprivation therapy, he
said. In addition, the researchers hope to look at the impact of the supplement
on other slow-growing cancers and even on cancer prevention.
The study received no funding
from the manufacturer of the supplement; however, the company worked very
closely with the research team to develop the product, said Williams.
"Unlike other nutritional supplement products, the manufacture of this
supplement was significantly more time-consuming because Dr. Thomas and
colleagues, for whom this was initially made, insisted on a great deal of
quality assurance, over and above that normally required by the US Food and
Drug Administration or European Commission, particularly in terms of purity and
authenticity."
He said the study signals "a
new era for the nutritional supplement industry, which has previously relied on
advertising and marketing rather than evidence of benefit. Clearly, it's the
latter that the public wants."